09:00 - 10:30 Session 2a: Inflammation
- Inflammation induced differentiation trajectories in human HSCs
E Laurenti (United Kingdom)
- Inflammation's epigenetic footprint in HSC
M Essers (Germany)
- Infection as a driver of epigenetic reprogramming and clonal competition of HSCs
K King (United States)
10:30 - 11:00 Coffee Break
11:00 - 12:00 Session 2b: Inflammation
- S201: Pre-leukemic Loss of Tet2 Perturbs Emergency Myelopoiesis Pathway Activation
J Swann (United States)
- S202: RNA degradation pathways are novel targets in acute myeloid leukaemia and regulators of the haematopoietic stem cell inflammatory response
C Mapperley (United Kingdom)
- S203: Emergency granulopoiesis induces a lymphoid to myeloid transcriptional switch in a subset of hematopoietic stem cells marked by CD201 expression
K Vanickova (Czech Republic)
12:00 - 13:00 Lunch break
13:00 - 14:30 Session 3a: Epigenome
- Mechanisms from pre-leukemic state to leukemia
U Steidl (United States)
- S503: Bnip3lb-regulated mitophagy maintains the embryonic HSPC pool via protection from ROS-induced apoptosis and differentiation
T North (United States)
- Systematic functional screening of chromatin factors identifies strong lineage and disease dependencies in normal and malignant hematopoiesis
B Huntly (United Kingdom)
14:30 - 15:30 Session 3b: Epigenome
- S301: Epigenetic programming predicts hematopoietic stem cell fate restriction and platelet
Y Meng (United Kingdom)
- S302: TET2 lesions enhance the aggressiveness of CEBPA mutant AML by restraining GATA2 expression
A Wilhelmson (Denmark)
- S303: Loss of the H2B deubiquitinase USP22 elicits systemic emergency hematopoiesis and enhances innate immunity
N Dietlein (Germany)
15:30 - 16:00 Coffee Break
16:00 - 17:30 Session 4a: Microenvironment
- Spatial Organization of Myelopoiesis
D Lucas (United States)
- Responses of the BM niche to stress
C Lo Celso (United Kinbgdom)
17:30 - 18:30 Poster Walk & reception
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